Invokana Ketoacidosis Kidney Failure Attorney
If you or somebody you know was diagnosed with diabetic ketoacidosis, or kidney failure after using Invokana, you should contact our attorneys immediately for a free case consultation.
Please use the form to contact our Defective Drug Litigation Team or call us toll-free 24 hours a day at (888) 210-9693 ext. 2 or 214-390-3189.Invokana is a Diabetic Medication
Johnson & Johnson’s Janssen Pharmaceuticals unit manufactures and distributes Invokana (canagliflozin), for folks with type-2 diabetes, to control their blood-sugar levels.Invokana Mechanism of Action
The FDA approved Invokana in 2013, and Invokana was the first medication in a new class known as sodium-glucose cotransporter-2 (SGLT2) inhibitors.
Other members of this class include Farxiga, Invokamet, Glyxambi, Jardiance, and Xigduo XR.
Invokana is the most widely used of the class. These medications prevent hyperglycemia (high blood-sugar levels) by allowing the kidneys remove excess blood sugar via the urine.What is the problem with Invokana?
According to a report from the Institute for Safe Medication Practices (ISMP), Invokana has been linked to hundreds of severe adverse events.
The FDA has received over 457 adverse events for Invokana in its first 12 months on the market, including:
- Kidney failure or damage
- Kidney stones
- Fluid/electrolyte problems
- Urinary tract infections
In December 2015, the FDA issued a Safety Communication for all drugs in the SGLT2 inhibitor class, including Invokana, after receiving many reports of patients who developed diabetic ketoacidosis.
New warning labels will be required for Invokana, Invokamet, Farxiga, Glyxambi, Jardiance, and Xigduo XR, which urge patients to look for signs of the DKA condition and to seek immediate medical attention if symptoms are present.
Patients were advised by the FDA to stop taking Invokana and seek medical attention immediately if they have any symptoms of ketoacidosis, a condition when the body produces high levels of blood acids called ketones.
In June 2016, the FDA required additional label warnings about the link between Invokana and kidney risks, highlighting that the medication may increase the risk of acute kidney injury.Invokana doubles Amputation risk of toes, feet, and legsBased on new data from two large clinical trials, the FDA in May 2017 concluded that the type 2 diabetes medicines Invokana, Invokamet, Invokamet XR caused an increased risk of leg and foot amputations.The FDA added new warnings including their most prominent Boxed Warning, to the Invokana drug labels to describe this risk.As patients become aware of the amputee side effects, injured patients are filing product liability lawsuits that claim that Invokana directly caused the amputation of their leg, foot or toes.What is Diabetic Ketoacidosis?
Diabetic ketoacidosis (DKA) is a serious complication of diabetes that occurs when the body produces high levels of blood ketones.
DKA develops when the body is unable to produce enough insulin. Insulin plays a key role in helping sugar (glucose) — a major source of energy for the muscles and other tissues — enter the cells.
Without enough insulin, the body begins to break down fat as an alternate fuel source. This process produces a buildup of toxic acids in the bloodstream called ketones, eventually leading to diabetic ketoacidosis if untreated.What are Diabetic Ketoacidosis Symptoms?
- Decreased alertness
- Deep, rapid breathing
- Dry skin and mouth
- Flushed face
- Frequent urination or thirst that lasts a day or more
- Fruity-smelling breath
- Muscle stiffness or aches
- Nausea and vomiting
- Stomach pain
If you or somebody you know was diagnosed with diabetic ketoacidosis, or kidney failure after using Invokana, you should contact our attorneys immediately for a free case consultation. Please use the form to contact our Defective Drug Litigation Team or call us toll-free 24 hours a day at (888) 210-9693 ext. 2.
Our law firm’s principal office is in Dallas and we have offices in Fort Worth, Texas. Dr. Shezad Malik Law Firm represents clients in dangerous drug and dangerous medical device lawsuits nationwide.